IAS Mains Previous Years Paper : Medical Sciences (1994)

PAPER - I

1. Answer any three of the following (each in about 200 words):
(a) Describe the mode of spread of cancer. (20)
(b) Name the viruses which are sexually transmitted. What are the possible mechanisms by which HIV destroys the immune cells of the body? (20)
(c) Define basal metabolic rate (BMR). Discuss the factors that influence the BMR of a subject. (20)
(d) What are the clinical conditions where morphine or morphine like drugs are used and state two important symptoms/ signs for recognition of its overdosage? (20)
(e) Describe the main events in the development of heart and explain its common cogenital anomalies. (20)
(f) Enumerate the various therapeutically useful penicillins. Write briefly on mode of action, antibacterial spectrum, therapeutic uses and common adverse effects of these antibiotics. (20)

SECTION A
(Anatomy, Physiology & Biochemistry)
2. (a) Define cardiac output. How can it be measured? Discuss the factors controlling it. (20)
(b) What are vitamins? Name the diseases produced by the deficiency of vitamin A, vitamin C, vitamin D, vitamin B, and vitamin B12. What are the functions of vitamin E? (20)
(c) Draw and label a cross-section (horizontal section) of abdomen passing through both the kidneys. (20)

3. (a) How is glucose homeostasis maintained in the body? (20)
(b) What are enzymes? Discuss the factors that affect the enzyme activity. (20)
(c) Define and enumerate broncho-pulmonary segments. What is their clinical significance? (20)

SECTION B
(Pathology & Microbiology)
4. (a) Define inflammation. Describe the vascular phenomenon of the inflammation. (30)
(b) Name the bacterial diseases which are transmitted by contaminated water. Describe the laboratory diagnosis of typhoid fever and the precautions to be undertaken in the interpretation of laboratory results. (30)

5. (a) Write in brief about aetiopathogenesis and histopathology of alcoholic cirrhosis.(30) 
(b) Define sterilization and mention the various physical methods of sterilization and their applications. (30)

SECTION C
(Pharmacology Forensic Medicine & Toxicology)
6. Discuss in detail the general principles of treatment of barbiturate poisoning. (60)

7. (a) Write in brief about the significance of DNA fingerprinting in personal identification. (20)
(b) What is the mode of action of beta-blockers in lowering blood pressure? (20)
(c) What are clinical manifestations of organo-phosphorus poisoning and what antidote will you use in this poisoning? (20)

PAPER - II
1. Write short notes on any three of the following (each in about 200 words) : (3 x 20 = 60)
(a) Peripheral blood picture in Chronic Myeloid Leukaemia
(b) Complications of varicose veins in the lower extremity
(c) Methods of induction of labour
(d) Important National Mortality Indicators

SECTION A
(General Medicine)
2. Discuss the complications of Diabetes Mellitus ? (60)

3. (a) What is the mode of transmittion of Human Immunodeficiency Virus ? How will your prevent its spread. (20)
(b) Discuss the etiology and complications of Portal Cirrhosis. (20)
(c) Describe the treatment of an acute case of Bronchial Asthma. (20)

SECTION B
(General Surgery)
4. What are the various causes of retention of urine? Describe the management of a case of retention of urine due to stage II benign hypertrophy of prostate. (60)

5. (a) Discuss the complications of Gall bladder disease. (20)

(b) 'What do you understand by the term 'Adynamic Intestinal Obstruction'? Describe the principles of management of such a case. (20)
(c) What are the broad principles in the management of a case of Fracture Spine? (20)


SECTION C
(Obstetric and Gynecology including Family Planning)
6. Define high risk pregnancy. Discuss the management of a primigravida at 36 weeks of gestation with BP of 150/100 mm Hg and one plus albuminuria. (60)

7. (a) How will you investigate the female partner in a couple with primary infertility? (20)
(b) Enumerate the various sexually transmitted diseases. Discuss the management of Trichomonal vaginalis infection.(20)
(c) Discuss the various methods for medical termination of pregnancy during second trimester. (20)

SECTION D
(Preventive and Social Medicine)
8. Describe the type of epidemiological study you will plan to determine the prevalence of risk factors of Coronary heart disease in the urban adults. 60
9. (a) Enumerate the components of Primary Health Gare. Briefly describe the principles underlying the Primary Health Care. (20)
(b) A two year old child has grade II Protein Energy Malnutrition. How will you manage such a case?  (20)
(c) A 35 year old man seeks employment in an Asbestos factory. As the Medical Officer-in charge, how will you assess his suitability for the job? Discuss. (20)