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(GIST OF SCIENCE REPORTER) GENOME INDIA PROJECT
(GIST OF SCIENCE REPORTER) GENOME INDIA PROJECT
(FEBRUARY-2025)
GENOME INDIA PROJECT
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The Department of Biotechnology recently announced its new platform and framework for sharing its 10,000 human genome dataset.
Key Details
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The sequences of healthy individuals from 99 ethnic populations of the country has helped create a baseline map of India’s genetic diversity.
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The researchers in the second phase plan to sequence genomes of those with specific diseases.
About Genome India Project
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The Genome India project was first approved in 2020 with the aim of capturing this diversity at the genomic level.
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Researchers from 20 different scientific institutions have come together to sequence the first 10,000 genomes under the project.
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The department of biotechnology aims to expand the programme further and sequence up to 1 million genomes.
How will data be shared
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The data will be available to Indian researchers through managed access. This is the first time that we have created a resource such as this and we have to be very careful how we share this highly sensitive data.
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Access will be granted only to research institutions that partner with us for the study.
Advantage of Genome India Project
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Inform Policy Decisions: Genetic data will help policymakers design and implement health strategies suited to India’s diverse population.
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Identify factors for diseases: The project will help identify genetic basis or genetic risk factors for various diseases. These can then be used as targets for developing therapies and diagnostic tests.
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Find new variants: An Indian dataset helps identify new variants. The researchers have identified 135 million genetic variations in the 10,000 genomes so far, 7 million of which are not found in the global databases.
Identify frequency of Genetic Variations: Population level sequencing can also tell scientists and clinicians the frequency at which certain genetic variations that are known to cause disease appear and hence how common a disease might be.
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Courtesy: Science Reporter