(GIST OF SCIENCE REPORTER) SPArc THERAPY


(GIST OF SCIENCE REPORTER) SPArc THERAPY

(JULY-2025)


SPArc THERAPY

Context:

Recently, a team of experts from the US has successfully used Step-and-Shoot-Spot-Scanning Proton Arc therapy (SPArc) to treat a 46-year-old patient suffering from adenoid cystic carcinoma.

What is SPArc Therapy?

  • SPArc is an advanced form of proton therapy that uses precisely targeted proton beams to destroy cancer cells while minimizing damage to surrounding healthy tissues.

Key Features and Mechanism

  • Precision Targeting: SPArc employs a scanning nozzle to deliver proton beams layer by layer, focusing on the tumour and sparing surrounding tissues.

  • Layered Energy Delivery: A computer program maps all possible locations and energy layers where proton beams can be directed. Each energy layer represents a section of tissue exposed to protons with a specific energy level. After delivering radiation to one layer by sweeping across multiple targeted spots, the device moves to the next energy level with a slightly deeper range and repeats the process.

  • Mode of Action: Radiation damages the DNA (deoxyribonucleic acid) of cancer cells, either killing them or inhibiting their growth.

  • Clinical Significance: SPArc is especially beneficial in cases of large or complex tumours, where it can precisely target malignant cells with minimal collateral damage to adjacent healthy tissues.

Advantages over Traditional Techniques (SFO-IMPT):

SPArc therapy significantly reduces radiation exposure to critical organs:

  • Brainstem: Reduced by 10%

  • Optic Chiasm: Reduced by 56% ¾ Oral Cavity: Reduced by 72%

  • Spinal Canal: Reduced by 90%

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Courtesy: Science Reporter