(Paper) UPSC MODEL PAPER PATTERN 2008-09 (General ability, General medicine, Paediatrics) Paper - 2

PAPER : UPSC MODEL PAPER PATTERN 2008-09

Paper-I

• General ability
• General medicine
• Paediatrics
  

41.In apatient of nephrotic syndrome with spontaneous bacterial peritonitis,which one of the following micro-organism in most commonly involved?
a.proteus
b.Escherichia
c.pneumococcus
d.staphylococcus


42.Which of the following renal injuries is characteristic of lithium toxicity ?
a.acute tubulointerstitial nephritis
b.acute tubular necrosis
c.nephrogenic DI
d.proliferative GN


43.Nephrotic syndrome is characterised by a/e:
a.hypoalbuminemia
b.hypolipidemia
c.lipiduria
d.prturia >3.5 gm/1.73 m2 /24 hrs


44.A 45 yr old female having headach of one week duration was found to have tender thickened cordlike structure on the scalp & high ESR.what is the most likely diagnosis?
a.tension headach
b.migrain
c.temporal arteritis
d.Tb meningitis


45.Following are components of POLYSOMNOGRAPGY except:
a.ECG
b.electrooculography
c.arterial carbon dioxide monitoring
d.pulse oximetry

46.Which one of the following tumor spread commonly to meninges?
a.astrocytoma
b.medulloblastoma
c.meningioma
d.glioblastoma

47.Site of lesion in Wallenberg syndrome:
a.lateral medulla
b.medial medulla
c.pontomedullary juction
d.dorsal midbrain

48.Drug that can induce parkinsonism include a/e:
a.reserpine
b.metoclopromide
c.trihexyphenidyl
d.haloperidol

49.Which of the following condition is MC cause of seizure in late infancy & early adulthood?
a.febrile seizure
b.seizures due to CNS TB
c.hypoglycemic seizures
d.hypocalcemic seizures

50.Which one of the following is a subcortical dementis :
a.Alzheimer’s disease
b.huntington’s chorea
c.normal pressure hydrocephalus
d.vit B12 deficiency

51.A middle aged male presents with sudden onset ipsilateral 6th N.palsy,ipsilateral infranuclear facial palsy & contralateral hemiplegia.Which one of the following syndromes is most likely ?
a.Wallenberg syndrome
b.Claude’s syndrome
c.weber’s syndrome
d.millard-gubler’s syndrome

52.Which one of the following is the MC immunologic type of multiple myeloma:
a.IgG kappa light chain
b.TgA kappa light chain
c.IgD lambda chain
d.IgM type

53.Which one of the following is not a feature of polycythemia vera?
a.elevated red cell mass
b.normal arterial oxygen saturation
c.splenomegaly
d.elevated plasma erythropoitin levels

54.Translocation of bcr-abl gene is charachteristic of :
a.CML
b.AML
c.CLL
d.ALL


55.Which one of the following is a known stimulus to production of erythropoitin :
a.hypoxia
b.hypercarbia
c.decompensated kidney disease
d.interleukin-3


56.An adult who develops pure red cell aplasia shud be explicitly evaluated for which of the following:
a.carcinoid syndrome
b.lymphoma
c.thymoma
d.seminoma


57.Which one the following is not true of henoch-Schonlein purpura?
a.polyarthralgia
b.cure of disease by steroids
c.hematuria
d.acute abdominal pain


58.Which one the following drugs has a structure that is analogous to thyroxine & contains huge amt of iodine?
a.clofibrate
b.colistipol
c.acetazolamide
d.amiodarone


59.Conditions a/w hypercalcemia with low PTH include a/e:
a.sarcoidosis
b.bronchial carcinoma
c.plasmacytoma
d.multiple endocrine neoplasia


60.Following are features of primary adrenal insufficiency except:
a.low serum ACTH
b.hyponatremia
c.hyperkalemia
d.hypotension


61.Hyperkalemia may be observed in following conditions except:
a.renal failure
b.primary hypoaldosteronism
c.cushing’s syndrome
d.cyclosporin therapy


62.Which one of the following is not likely to be a feature in a pt. With secondary hypothyroidism?
a.low free T4
b.low TSH
c.low ACTH
d.low prolactin


63.Which of the following is not true about bulimia nervosa?
a.invariable wt loss with endocrine disorder
b.occurance of both binge eating & inappropriate compensatory behaviour at least twice weekly,on an average,for 3 months
c.recurrent episode of binge eating
d.recurrentself induced vomiting

64.Which one of the following is a/w shift of potassium into cells:
a.calcium gluconate administration
b.IV frusemide
c.dialysis
d.salbutamol inhalation


65.Which one of the following features is not true about Wilson’s disease?
a.hepatolenticular degenration
b.auto.recessive transmission
c.sr.ceruloplasmin increased
d.urinary copper increased


66.Which one of the following statement is correct :
a.Most of the individuals with chronic hyperuricemia develops gout
b.90% of pt. With gout have undersecretion of uric acid
c.gout mostly affcet premenopausal women
d.DOC for acute gout is Allopurinol


67.A 40 yr old man presents with loss of libido,lethargy,headach & galactorrhoea.He is most likely suffering from :
a.testicular atrophy
b.hyperprolactenaemia
c.addison’s disease
d.adult hypopituitarism


68.EB virus has been a/w the following disorder except:
a.burkitt’s lymphoma
b.nasopharyngeal carcinoma
c.hairy cell leukemia
d.oral hairy leukoplakia


69.Which of the following statement is true about TB in an HIV-infected pt?
a.upper lobe pulmonary cavity disease is an unusual manifestation on TB
b.extra pulmonary TB is an unusual manifestation of TB
c.HIV infected pt. With pulmonary TB are usually diagnosed with positive sputum smears
d.TB is MC cause of meningitis


70.Human is the reservoir for which one of the following rickettial disease?
a.epidemic typhus
b.rocky mountain spotted fever
c.endemic typhus
d.scrub typhus


71.Lepromatous leprosy is consistent with the following except:
a.Type II lepra reaction can occur
b.inflammatory reaction is sparse
c.loss of sensation occurs late
d.surface of the skin lesion is smooth & shiny


72.Following are considered as stigmata of congenital syphillis except:
a.Hutchinson’s incisors
b.saddle nose
c.aortic regurgitation
d.sabre tibia


73.Following drugs have been found to be useful in primary pulmonary hypertension except:
a.calcium channel blocker
b.prostacyclins
c.beta blockers
d.sildenafil


74.Preferred drug for treatment of hypertension in pregnancy:
a.enalapril
b.prazocin
c.indapamide
d.alpha methyl dopa

75.Following is an anticonvulsant of choice for alcohol withdrowl seizures?
a.phenytoin
b.sodium valproate
c.carbamazepine
d.benzodiazepine


76.INH toxicity may cause the following except:
a.psychosis
b.nephropathy
c.hepatitis
d.peripheral neuropathy


77.Praziquantel is an effective drug to treat the following conditions except:
a.shistosomiasis
b.cysticercosis
c.hydatid disease
d.trichinosis


78.Which of the following is not consistent with pellagra?
a.pellagra can occur in carcinoid syndrome
b.diarrhoea & dementia are usual features
c.casal’s necklace may be seen around the neck & upper chest
d.response to niacin can be very low in early stages


79.Causes of pruritus in 3rd trimester of pregnancy include a/e:
a.prurigo gestationis
b.obstetric cholestasis
c.pemphigoid gestationis
d.pruritic folliculitis

80.Following disease can cause [bleep] lesions in skin except:
a.pemphigus
b.impetigo
c.toxic epidermal necrolysis
d.pityriasis rosea